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But the majority will probably still need some dose of the drug because the [food] environment is still the same." There's also increasing concern that individuals are taking weight-loss medication as a substitute for making life-style changes even though evidence shows that modifying lifestyle in combination with weight-loss drugs is what will lead to greater weight loss

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Hepatic hydroxyproline content was measured using a commercially available Total Collagen Kit (Quickzyme Biosciences, Leiden, Netherlands) according to the manufacturers instructions